Injectables

REJURAN + TARGETCOOL Skin Rejuvenation

Now available in Fajardo and San Juan, REJURAN® + TargetCool offer a non-invasive way to renew your skin. This advanced combo boosts collagen, soothes inflammation, and improves texture—without downtime. Perfect for those seeking natural, glowing results with cutting-edge care.

What is REJURAN® + TargetCool?

REJURAN® is a revolutionary skin rejuvenation treatment developed in Korea. It uses polynucleotides (PN) extracted from salmon DNA to repair damaged skin, improve elasticity, and boost hydration. Often called the “Healer of Skin,” REJURAN works at the cellular level to restore the skin’s natural structure and youthfulness.

TargetCool® is a precision cooling device that uses cryotechnology to minimize pain, redness, and inflammation during and after aesthetic procedures. It enhances comfort during REJURAN injections and accelerates healing for an even better outcome.

When combined, these treatments offer powerful results with less discomfort, faster recovery, and beautifully rejuvenated skin.

What to Expect During Treatment

After a personalized skin consultation, our provider will apply TargetCool to numb and prep your skin. Then, REJURAN is precisely injected into targeted areas. The entire session lasts about 30–45 minutes. You may experience slight redness or bumps for a few hours, but most clients return to their day right away.

How Many Sessions Will I Need?

A series of 3–4 sessions spaced 3–4 weeks apart is typically recommended for best results. Maintenance treatments may be suggested every 6–12 months.

Is It Safe?

Yes. REJURAN is made from biocompatible, purified polynucleotides, and TargetCool uses a controlled cryo-delivery method approved for clinical use. This combination is safe for most skin types and ideal for anyone looking for a natural, non-invasive boost. Results You Can Expect
  • Softer, smoother skin texture
  • Improved tone and radiance
  • Reduced redness and inflammation
  • Stronger, more resilient skin barrier
  • Long-term collagen stimulation
Results begin to appear within 1–2 weeks, improving steadily over time.

Benefits of REJURAN® + TargetCool

REJURAN naturally stimulates collagen regeneration at the cellular level for firmer, smoother skin over time.

TargetCool calms skin during treatment and reduces redness, making it ideal for sensitive or post-acne skin.

Enjoy noticeable skin rejuvenation with no surgery, no harsh chemicals, and minimal downtime.

Smooth out rough patches, minimize pores, and reveal a healthy, radiant glow.

Cryo-cooling from TargetCool helps reduce recovery time and speeds up visible improvements.

Biocompatible ingredients and controlled technology make this duo safe and effective for a wide range of skin concerns.

Why Choose Cure Aesthetics Clinic for REJURAN® + TargetCool?

  • Dual-Therapy Expertise: We specialize in pairing REJURAN’s regenerative properties with TargetCool’s advanced cryo technology for enhanced results.
  • Minimized Discomfort: Our use of TargetCool ensures your treatment is more comfortable, with reduced sensitivity, redness, and swelling.
  • Tailored Treatment Plans: Every client receives a personalized approach based on skin type, goals, and sensitivities to maximize outcomes.
  • Licensed Professionals: All treatments are performed by trained and certified medical professionals experienced in advanced aesthetic therapies.
  • Convenient Locations: Available at both our Fajardo and San Juan locations, making it easy to access expert care near you.
  • Natural, Long-Term Improvements: We focus on helping your skin restore itself naturally—no overfilled look, just healthy, glowing results.

Our Board-Certified Doctor

5 star google reviewsRead our Five-Star Reviews on Google 

  • Slide Image
    Lizbeth Enchautegui Client

    100% recommended. I am extremely pleased and grateful to Dr. Caraballo for her excellent work and the quality service she provided me.

  • Slide Image
    Gio Mateo Client

    Perfect attention, super friendly and very good at his job. Thanks a lot. Pleased with the results!

  • Slide Image
    JAHV ARQUITECTURA Client

    The place has comfortable and accessible parking. Elegant office. Exceptional treatment from the doctor.

  • Slide Image
    Rosary Gonzalez Client

    Excellent service and professionalism, I recommend Dr. Caraballo, very satisfied with her work.

  • Slide Image
    Waleska Rodriguez-Carrasquillo Client

    Excellent. Personalized and professional service.

  • Slide Image
    Carmen Sanchez Client

    I love the place, a lot of professionalism and, above all, courtesy.

  • Slide Image
    Yolaimnys Pujols Client

    The best attention 100% recommended and all highly trained staff.

  • Slide Image
    Ileana Carrion Client

    Excellent! The best!!

  • Slide Image
    Kamila Vazquez Client

    The best!! Recommended to 💯

  • Slide Image
    Irma Pastrana Client

    Recommended 100%

  • Slide Image
    Linet Rodriguez Client

    Great!

  • Slide Image
    Janice Pedraza Client

    Great!

have a question?

Quick answers to questions you may have

Minimal. Redness or swelling may last a few hours post-treatment.

Not at all. TargetCool numbs the area, making the experience nearly painless.

Initial results are visible in 1–2 weeks, with continued improvement over months.

Yes! REJURAN and TargetCool pair beautifully with microneedling, dermal fillers, and botulinum therapy.

Ready to Experience the Power of REJURAN® + TargetCool?

Reveal smoother, healthier, more youthful-looking skin with our advanced dual therapy. Whether you’re targeting fine lines, enlarged pores, or overall skin texture, this innovative combination treatment delivers visible, lasting results with minimal downtime.

Book your consultation today at Cure Aesthetics Clinic in Fajardo or San Juan and let our expert team create a personalized plan just for you. Your best skin starts here.

Book Appointment at Fajardo Location
Book Appointment at San Juan Location